Oligonucleotide Scientist

Post Date

Mar 10, 2026

Location

Upper Leacock,
Pennsylvania

ZIP/Postal Code

17601
US
May 11, 2026 Insight Global

Job Type

Perm

Category

Materials Science & Engineering

Req #

KPD-9d936fc4-0a26-48a8-b7ad-804a1bd8828c

Pay Rate

$100k - $115k (estimate)

Job Description

Insight Global is looking for a resource to support testing of oligonucleotide drug substances and products by developing and running analytical methods. The primary focus is on HPLC/UHPLC and mass spectrometry to confirm identity, measure purity and impurities, support stability studies, and ensure accurate results.

The scientist will write and maintain methods and reports, ensure data quality and compliance in regulated (GxP) environments, lead routine testing and investigations, and help mentor junior team members.

This role will be one of the first high level technical experts to grow and drive the technical knowledge of the Biopharma division.

We are a company committed to creating diverse and inclusive environments where people can bring their full, authentic selves to work every day. We are an equal opportunity/affirmative action employer that believes everyone matters. Qualified candidates will receive consideration for employment regardless of their race, color, ethnicity, religion, sex (including pregnancy), sexual orientation, gender identity and expression, marital status, national origin, ancestry, genetic factors, age, disability, protected veteran status, military or uniformed service member status, or any other status or characteristic protected by applicable laws, regulations, and ordinances. If you need assistance and/or a reasonable accommodation due to a disability during the application or recruiting process, please send a request to HR@insightglobal.com.To learn more about how we collect, keep, and process your private information, please review Insight Global's Workforce Privacy Policy: https://insightglobal.com/workforce-privacy-policy/.

Required Skills & Experience

- 5-10+ years of hands‑on lab experience

- Strong background in oligonucleotide analytical testing/method development (design, develop, optimize, execute, troubleshoot)

- Hands‑on expertise with HPLC/UHPLC and Mass Spectrometry (LC‑MS, LC‑MS/MS)

- Deep understanding of molecular behavior and analytical testing strategies

- Experience working in GxP‑regulated environments

- Comfortable in a client‑facing role

Nice to Have Skills & Experience

- Experience mentoring or guiding junior scientists/analysts

- Experience with peptides

Benefit packages for this role will start on the 1st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.