Our large pharmaceutical client in Spring House, PA is seeking a Scientist to join their growing team within the Oncology Discovery area specifically within Immuno-Oncology Targeted Therapy. This individual will be joining the drug discovery program to develop cutting-edge therapeutics for the treatment of cancer and will work in an exciting/stimulating environment across the different stages of preclinical drug discovery. Responsibilities include:
-Execute multiple cell biology assays that could include Western blotting, flow cytometry, cell proliferation, cellular cytotoxicity, cell culture, transfection/transduction, immunoprecipitation.
-Design & perform experiments including target validation and assay development in solid tumors, for advancement of programs in the portfolio and new targets.
-Utilize graphing software such as Graph Pad and interpret complex data, rework experiments based on interpretations and propose next steps.
-Summarize and present data to larger team as well as leadership.
-Work in a collaborative environment and demonstrate organization and urgency.
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-Bachelor's or Master's degree in biology or related
-3-5+ years of lab-based industry experience
-Cell culture experience (human cell lines)
-Execution of cell biology assays, particularly flow cytometry (5-6 color panels), Western Blot, Cytotoxicity and cell-killing assays
-Incucyte experience
-Drug dilution experience
-T-cell killing experience
-Oncology research background
Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.