One of our large pharmaceutical clients is seeking an Associate Scientist their dynamic team within Immunology Translational Sciences group in Spring House, PA. The Immunology Translational Sciences team uses human based data and tissues to support the end-to-end portfolio. TS has a broad remit stretching from support of discovery with human data to target selection, through development of novel decision-making biomarkers for early phase clinical trials, target-centric indication sequencing and prioritization, and biomarker support of regulatory filings. The group has expertise in biomarker development, disease biology research and in the application of immunology and data science technologies to support drug discovery and development.
The new hire will develop and execute in vitro and ex vivo assays to support translational research for Immunology portfolio programs. This position requires a highly motivated and skilled candidate that can operate in a collaborative environment with members of Translational Sciences and partner organizations. The Associate Scientist will be responsible for the execution of high caliber biomarker plans, assay development and validation, and associated data generation from early and late-stage clinical studies.
Key responsibilities:
-Support biomarker assay development and execution using flow cytometry, ELISA, MSD/SMC, spatial protein/RNA (e.g., DSP), RNA/DNA purification, qPCR, and/or tissue culture
-Design and execute experiments to discover new biomarkers and/or assays for portfolio assets
-Analyze data and communicate results to project team in a timely manner
-Partner with external partners as needed to support Immunology portfolio programs
-Work closely with other lab-based personnel to ensure optimal laboratory environment (collaboration, culture, safety, etc.)
-Work independently and manage multiple projects simultaneously under fixed timelines
-Contribute to the preparation of and submission of technical reports, prepare clear and concise summaries, and present to project teams and colleagues
-Take initiative to identify, pilot and internalize emerging technical approaches that may drive increased value for portfolio execution
-Deliver on study milestones and commitments and foster a collaborative, creative, and rigorous culture of scientific discovery
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-B.A./B.S. with 4+ years related experience OR M.S. with 1-2 years research experience (academic or industry)
-Hands on experience with Flow Cytometry
-Strong ELISA assay experience
-Experience with in vitro and/or ex vivo assays
-Biomarker assay development and validation and clinical sample analysis
Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.