Principal Investigator

Insight Global is hiring a Principal Investigator responsible for ensuring Good Clinical Practice (GCP) in the conduct of clinical investigations and full compliance with protocols, regulations, and guidance documents.
This role oversees all medical and safety-related activities for clinical research studies IRB-approved protocols, protecting subject rights and ensuring data integrity.
The Principal Investigator will lead, train, supervise, and delegate to a multidisciplinary team of physicians, physician assistants, nurse practitioners, and Sub‑Investigators.
Responsibilities include providing medical oversight, protocol feasibility input, SOP and safety procedure development, and consultation throughout study execution.
The role involves direct sponsor engagement, including capability presentations, bid defense meetings, and review of clinical trial protocols and study reports.
The Principal Investigator will assess subject eligibility, perform physical examinations, review medical histories and laboratory results, and obtain and document informed consent.
They are accountable for evaluating, documenting, and reporting adverse events, serious adverse events, pregnancies, and clinically significant findings to sponsors, IRBs, and applicable authorities.
Maintaining accurate, complete, and inspection-ready records, including case report forms and safety data, is essential to the success of this position.

We are a company committed to creating diverse and inclusive environments where people can bring their full, authentic selves to work every day. We are an equal opportunity/affirmative action employer that believes everyone matters. Qualified candidates will receive consideration for employment regardless of their race, color, ethnicity, religion, sex (including pregnancy), sexual orientation, gender identity and expression, marital status, national origin, ancestry, genetic factors, age, disability, protected veteran status, military or uniformed service member status, or any other status or characteristic protected by applicable laws, regulations, and ordinances. If you need assistance and/or a reasonable accommodation due to a disability during the application or recruiting process, please send a request to HR@insightglobal.com.To learn more about how we collect, keep, and process your private information, please review Insight Global's Workforce Privacy Policy: https://insightglobal.com/workforce-privacy-policy/.

• Valid MD license, with the ability to practice in Ontario
• Good standing with CPSO, CMPA or equivalent coverage
• BCLS/ACLS certification under AHA.
• Experience conducting phase I-II trials and BA/BE studies.
• 8-12 years of experience in clinical research.
• 8-12 years of drug development and clinical trial administration
• Knowledge Federal and/or international guidelines and regulations,

Ability to be flexible and adapt to and manage constant changes in priorities and
projects.
• Expert and up to date knowledge of:
o Clinical trials,
o Drug development,
o Medical monitoring experience,
o Knowledge of medical coding and systems for adverse event review and
reporting is preferred, and,
o Pharmacokinetics.

Benefit packages for this role will start on the 1st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.